The activity of doxorubicin niosomes against an ovarian cancer cell line and three in vivo mouse tumour models.

@article{Uchegbu1996TheAO,
  title={The activity of doxorubicin niosomes against an ovarian cancer cell line and three in vivo mouse tumour models.},
  author={Ijeoma F. Uchegbu and John A. Double and L. R. Kelland and John A. Turton and Alexander T. Florence},
  journal={Journal of drug targeting},
  year={1996},
  volume={3 5},
  pages={
          399-409
        }
}
Demonstration of the improved doxorubicin pharmacokinetics and tumoricidal activity, after a single intravenous dose of 10mg kg-1 doxorubicin sorbitan monostearate (Span 60) based niosomes in the mouse adenocarcinoma (MAC) tumour model (Uchegbu et al., 1995) preceded the present study in which the activity of doxorubicin C16G2 (a hexadecyl diglycerol ether) based niosomes was evaluated against naive and established MAC tumour models. C16G2 niosomes were equiactive with doxorubicin solution. It… 
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