The activin-follistatin system and in vitro early follicle development in goats.

  title={The activin-follistatin system and in vitro early follicle development in goats.},
  author={Jos{\'e} Roberto V Silva and Theerawat Tharasanit and Marcel A M Taverne and Gijsbert C van der Weijden and R R Santos and Jos{\'e} Ricardo de Figueiredo and Robert van den Hurk},
  journal={The Journal of endocrinology},
  volume={189 1},
The aim of the present study was to investigate the effects of activin-A and follistatin on in vitro primordial and primary follicle development in goats. To study primordial follicle development (experiment 1), pieces of ovarian cortex were cultured in vitro for 5 days in minimal essential medium (MEM) supplemented with activin-A (0, 10 or 100 ng/ml), follistatin (0, 10 or 100 ng/ml) or combinations of the two. After culture, the numbers of primordial follicles and more advanced follicle… CONTINUE READING
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