The activation of protease-activated receptor 1 mediates proliferation and invasion of nasopharyngeal carcinoma cells.

Abstract

Protease-activated receptor 1 (PAR-1) is a G-coupled membrane protein, which is involved in physiological and malignant invasion processes. It is activated by serine proteases such as thrombin through a unique form or by specific synthetic peptides. In this study, we determined the expression of PAR-1 in five nasopharyngeal carcinoma (NPC) cell lines with… (More)
DOI: 10.3892/or.2012.1802

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