The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages

@article{Toln2009TheAO,
  title={The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages},
  author={Rosa Mar{\'i}a Tol{\'o}n and Estefan{\'i}a N{\'u}{\~n}ez and Mar{\'i}a Ruth Pazos and Cristina Benito and Ana Isabel Castillo and Jos{\'e} Mart{\'i}nez-Orgado and Juli{\'a}n Romero},
  journal={Brain Research},
  year={2009},
  volume={1283},
  pages={148-154}
}
The endocannabinoid system is a promising therapeutic target in a wide variety of diseases. However, the non-desirable psychotropic effects of natural and synthetic cannabinoids have largely counteracted their clinical usefulness. These effects are mostly mediated by cannabinoid receptors of the CB(1) type, that exhibit a wide distribution in neuronal elements of the CNS. Thus, the presence of other elements of this system in the CNS, such as CB(2) receptors, may open new possibilities for the… Expand
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