The activation of ERK1/2 and p38 mitogen-activated protein kinases is dynamically regulated in the developing rat visual system

@article{Oliveira2008TheAO,
  title={The activation of ERK1/2 and p38 mitogen-activated protein kinases is dynamically regulated in the developing rat visual system},
  author={Camila Salum De Oliveira and Ana Paula Rigon and Rodrigo Bainy Leal and Francesco Mattia Rossi},
  journal={International Journal of Developmental Neuroscience},
  year={2008},
  volume={26},
  pages={355-362}
}
Mitogen-activated protein kinases (MAPKs) are serine/threonine kinases that play an instrumental role in signal transduction from the cell surface to the nucleus. These enzymes are major intracellular mediators of developmental events and recently have been shown to control also synaptic plasticity processes [Sweatt, J.D., 2004. Mitogen-activated protein kinases in synaptic plasticity and memory. Curr. Opin. Neurobiol. 14, 311-317; Thomas, G.M., Huganir, R.L., 2004. MAPK cascade signalling and… CONTINUE READING

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