The actions of thioguanine in Bacillus cereus.

@article{Mandel1965TheAO,
  title={The actions of thioguanine in Bacillus cereus.},
  author={H. G. Mandel and R. Latimer and M. Riis},
  journal={Biochemical pharmacology},
  year={1965},
  volume={14 5},
  pages={
          661-82
        }
}
Abstract The effects of the guanine analog, 6-thioguanine, have been evaluated in exponentially growing cultures of Bacillus cereus . The drug produced growth inhibition instantly, the duration but not the degree of which was related to the inhibitor concentration. Guanine prevented completely thioguanine-induced growth inhibition, in a competitive manner, whereas adenine and hypoxanthine were incapable of abolishing the inhibitory actions. Although thioguanine was anabolized into the… Expand
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