The action potential in mammalian central neurons

  title={The action potential in mammalian central neurons},
  author={B. Bean},
  journal={Nature Reviews Neuroscience},
  • B. Bean
  • Published 2007
  • Biology, Medicine
  • Nature Reviews Neuroscience
  • The action potential of the squid giant axon is formed by just two voltage-dependent conductances in the cell membrane, yet mammalian central neurons typically express more than a dozen different types of voltage-dependent ion channels. This rich repertoire of channels allows neurons to encode information by generating action potentials with a wide range of shapes, frequencies and patterns. Recent work offers an increasingly detailed understanding of how the expression of particular channel… CONTINUE READING
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