The action of tributyltin on energy coupling in coupling-factor-deficient submitochondrial particles.

@article{Dawson1975TheAO,
  title={The action of tributyltin on energy coupling in coupling-factor-deficient submitochondrial particles.},
  author={Alan Dawson and Michael J. Selwyn},
  journal={The Biochemical journal},
  year={1975},
  volume={152 2},
  pages={
          333-9
        }
}
1. Tributyltin at concentrations of approx. 1nmol/mg of protein induces respiratory control and lessens the protein permeability of coupling-factor-deficient submitochondrial particles. 2. At these concentrations or lower, it increases the P/O ratio of the particles to a small extent and inhibits the adenosine triphosphatase activity without greatly increasing its sensitivity to uncoupling agents. 3. It fails to stimulate ATP-driven reversed electron transport or transhydrogenase, but… CONTINUE READING