The action of sympathetic blocking agents on isolated and innervated atria and vessels.

  • S. Huković
  • Published 1960 in British journal of pharmacology and chemotherapy


A preparation is described of isolated rabbit atria with both vagus and sympathetic nerves. The action on it of bretylium and of choline 2,6-xylyl ether bromide (TM10) was studied. A concentration of breylium sufficient to abolish the response to sympathetic stimulation also depressed the response to vagal stimulation. The effect was reversible, though more… (More)


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