Corpus ID: 27355713

The action of (R)- and (S)-alpha-chlorohydrin and their metabolites on the metabolism of boar sperm.

@article{Stevenson1984TheAO,
  title={The action of (R)- and (S)-alpha-chlorohydrin and their metabolites on the metabolism of boar sperm.},
  author={D. Stevenson and A. Jones},
  journal={International journal of andrology},
  year={1984},
  volume={7 1},
  pages={
          79-86
        }
}
  • D. Stevenson, A. Jones
  • Published 1984
  • Medicine
  • International journal of andrology
  • The action of (R,S)-alpha-chlorohydrin in inhibiting glycolysis in boar sperm is due to the (S)-isomer. Its effect on the concentrations of glycolytic intermediates suggests that the pathway is inhibited at the glyceraldehyde 3-phosphate dehydrogenase reaction. alpha-Chlorohydrin is oxidized by boar liver homogenates via 3-chlorolactaldehyde to 3-chlorolactate. Racemic mixtures of both compounds, and a proposed metabolite, 3-chloropyruvate, inhibit the oxidative metabolism of fructose, lactate… CONTINUE READING
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