The actin-binding proteins adseverin and gelsolin are both highly expressed but differentially localized in kidney and intestine.

@article{Lck1998TheAP,
  title={The actin-binding proteins adseverin and gelsolin are both highly expressed but differentially localized in kidney and intestine.},
  author={Andreas L{\"u}ck and Darren Brown and David J Kwiatkowski},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 24)},
  pages={
          3633-43
        }
}
To understand the distinct functions of the closely related actin-severing proteins adseverin and gelsolin, we examined the expression of these proteins in detail during mouse and human development using a new highly sensitive and specific set of antibody reagents. Immunoblot analysis demonstrated that adseverin was highly expressed in mouse kidney and intestine at all stages of development and in human fetal and adult kidney. In contrast and as reported previously, gelsolin was expressed much… CONTINUE READING
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