The acrosome reaction in digitonin-permeabilized sea urchin sperm in the absence of the natural inducer.


In many species, the acrosome reaction of sperm is an obligatory step in fertilization. Increases in [Ca2+]i and pHi, activation of adenylyl cyclase and inositol trisphosphate generation accompany the egg jelly-induced acrosome reaction of sea urchin sperm. The signaling mechanisms involved are unknown. We used digitonin, a cholesterol-complexing compound… (More)


  • Presentations referencing similar topics