The accuracy of several multiple sequence alignment programs for proteins

@article{Nuin2006TheAO,
  title={The accuracy of several multiple sequence alignment programs for proteins},
  author={Paulo A. S. Nuin and Zhouzhi Wang and Elisabeth R. M. Tillier},
  journal={BMC Bioinformatics},
  year={2006},
  volume={7},
  pages={471 - 471}
}
BackgroundThere have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" alignment is usually unknown due to the incomplete knowledge of the evolutionary history of the sequences, making it difficult to gauge the relative accuracy of the programs.ResultsWe tested nine of the most often used protein alignment programs and compared their results using sequences generated with the simulation software… CONTINUE READING

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