The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis.

  title={The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis.},
  author={M. Frank Termaat and Pieter G.H.M. Raijmakers and Harm J. Scholten and Fred C. Bakker and Peter Patka and Henk J. Th. M. Haarman},
  journal={The Journal of bone and joint surgery. American volume},
  volume={87 11},
BACKGROUND A variety of diagnostic imaging techniques is available for excluding or confirming chronic osteomyelitis. Until now, an evidence-based algorithmic model for choosing the most suitable imaging technique has been lacking. The objective of this study was to determine the accuracy of current imaging modalities in the diagnosis of chronic osteomyelitis. METHODS A systematic review and meta-analysis of the literature was conducted with a comprehensive search of the MEDLINE, EMBASE, and… 

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Imaging tests for the detection of osteomyelitis: a systematic review.

Osteomyelitis is reliably diagnosed by MRI, PET and SPECT, and no clear reason to prefer one test over the other in terms of diagnostic accuracy was identified.

A comparison of imaging modalities for the diagnosis of osteomyelitis

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The diagnostic imaging of osteomyelitis can require the combination of diverse imaging techniques for an accurate diagnosis. Conventional radiography should always be the first imaging modality to

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Radiological evaluation of postoperative osteomyelitis in long bones: Which is the best tool?

Currently, definitive diagnosis of osteomyelitis involves a combination of clinical signs, symptoms, laboratory tests, imaging modalities and cultures from blood, joint or body fluid. Imaging plays a

Magnetic Resonance Imaging for Diagnosing Foot Osteomyelitis

It is found that MRI performs well in the diagnosis of osteomyelitis of the foot and ankle and can be used torule outthediagnosis.

The Accuracy of Imaging Techniques in the Assessment of Periprosthetic Hip Infection: A Systematic Review and Meta-Analysis.

Of the currently used imaging techniques, leukocyte scintigraphy has satisfactory accuracy in confirming or excluding periprosthetic hip infection, but FDG PET may not yet be the preferred imaging modality because of limited availability and relatively higher cost.



Chronic complicated osteomyelitis of the lower extremity: evaluation with MR imaging.

Close correlation was found between the extent of disease seen on surgical and pathologic examination and that demonstrated by MR imaging, which could delineate the course of sinus tracts, which was helpful in assessing the activity of chronic complicated osteomyelitis and beneficial in surgical planning for these patients.

Chronic post-traumatic osteomyelitis of the lower extremity: comparison of magnetic resonance imaging and combined bone scintigraphy/immunoscintigraphy with radiolabelled monoclonal antigranulocyte antibodies

MRI is more sensitive in low-grade infection during the later course than combined BS/IS and can be excluded with high probability if the MRI findings are negative, while scintigraphic errors due to ectopic, peripheral, haematopoietic bone marrow can be corrected by MRI.

Chronic complicated osteomyelitis of the appendicular skeleton: Diagnosis with technetium-99m labelled monoclonal antigranulocyte antibody-immunoscintigraphy

It is concluded that combined BS/99mTc-MAB-IS represents a very sensitive and reproducible method with an acceptable specificity for the investigation of chronic OM.

Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells.

Although scintigraphy with indium-labeled white blood cells is quite sensitive, it is not specific in detecting chronic osteomyelitis; a negative scan should be considered highly suggestive that osteomyeliitis is not present.

99Tcm-HMPAO-labelled leucocyte scintigraphy in suspected chronic osteomyelitis related to an orthopaedic device: clinical usefulness.

It is concluded that HMPAO-LS should only be performed to assist in the diagnosis of chronic osteomyelitis when there is no preexisting strong suspicion based on clinical, biological and radiological signs.

Imaging of chronic posttraumatic osteomyelitis

An overview of definition, epidemiology, and pathophysiology of chronic posttraumatic osteomyelitis is given and the value of currently used imaging modalities is discussed.

Osteomyelitis: diagnosis with In-111-labeled leukocytes.

Overall sensitivity was significantly lower in the central location than in the peripheral or middle location, and the ability to determine that the infection was in bone rather than in adjacent soft tissue was greater with simultaneous bone scan and In-111 leukocyte studies than with sequential studies.

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Combined 99mTc-MDP/111In-WBC imaging is useful in the detection of osteomyelitis at fracture nonunion sites and improves the specificity of 111In- WBC imaging by differentiating inflammation/infection in adjacent soft tissue from osteomyalitis at the fracture site.

Radionuclide diagnosis of vertebral osteomyelitis: indium-111-leukocyte and technetium-99m-methylene diphosphonate bone scintigraphy.

Using increased or decreased activity as criteria for infection, the accuracy of leukocyte imaging for diagnosing vertebral osteomyelitis was 66%, similar to that of 99mTc bone imaging (63%) in the population.