The absolute bioavailability of caffeine in man

@article{Blanchard2004TheAB,
  title={The absolute bioavailability of caffeine in man},
  author={James Blanchard and STEWART J. A. Sawers},
  journal={European Journal of Clinical Pharmacology},
  year={2004},
  volume={24},
  pages={93-98}
}
SummaryThe absolute bioavailability of orally administered caffeine was investigated in 10 healthy adult male volunteers, aged 18.8 to 30.0 years. The subjects were administered a 5 mg/kg dose of caffeine as either an aqueous oral solution or an intravenous infusion, on separate occasions about 1 week apart, in a randomized crossover fashion. Plasma samples were collected over the 24-h period following each dose and assayed for their caffeine content using a high-performance liquid… 
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