The absence of mutations in homeobox candidate genes HOXA3, HOXB3, HOXD3 and PITX2 in familial and sporadic thyroid hemiagenesis.

Abstract

BACKGROUND The molecular mechanisms leading to the formation of the two thyroid symmetrical lobes, which are impaired in thyroid hemiagenesis (TH), are little known. OBJECTIVE The aim of this work was to search for mutations in thyroid developmental candidate genes HOXA3, HOXB3, HOXD3 and PITX2. METHODS Total DNA from peripheral blood was extracted and… (More)
DOI: 10.1515/jpem-2013-0289

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@article{Kizys2014TheAO, title={The absence of mutations in homeobox candidate genes HOXA3, HOXB3, HOXD3 and PITX2 in familial and sporadic thyroid hemiagenesis.}, author={Marina Malta Letro Kizys and Suzana Nesi-França and Mirian G Cardoso and Michelle Y Harada and Maria Clara de C Melo and Maria Izabel Chiamolera and Magnus R{\'e}gios Dias-da-Silva and Rui Monteiro de Barros Maciel}, journal={Journal of pediatric endocrinology & metabolism : JPEM}, year={2014}, volume={27 3-4}, pages={317-22} }