The abrupt transition from rest to activity in muscle

  title={The abrupt transition from rest to activity in muscle},
  author={Archibald Vivian Hill},
  journal={Proceedings of the Royal Society of London. Series B - Biological Sciences},
  pages={399 - 420}
  • A. Hill
  • Published 19 October 1949
  • Engineering
  • Proceedings of the Royal Society of London. Series B - Biological Sciences
The internal mechanical condition of an excited muscle has been examined by applying quick stretches at various moments after a maximal shock. At the end of the latent period there is an abrupt change of state, the contractile component suddenly becoming capable of bearing a load equal to the maximum tension set up in an isometric tetanus. The intensity of the active state produced by a shock is greatest at the start, is maintained for a time and then declines as relaxation sets in. The… 

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Part I is an account of experiments which prove that the same general type of relation between work and speed of shortening occurs in isolated muscle, and the phenomera investigated are not due primarily to an intervention of the nervous system, but to some fundamental character of the muscle fibre itself.