The ability of biomarkers to predict systemic progression in men with high-risk prostate cancer treated surgically is dependent on ERG status.

@article{Karnes2010TheAO,
  title={The ability of biomarkers to predict systemic progression in men with high-risk prostate cancer treated surgically is dependent on ERG status.},
  author={Robert Jeffrey Karnes and John C. Cheville and Cristiane Marie Ida and Thomas J. Sebo and Asha A. Nair and Hui Tang and J Munz and Farhad Kosari and George Vasmatzis},
  journal={Cancer research},
  year={2010},
  volume={70 22},
  pages={8994-9002}
}
The objective of this study was to assess the relationship of the tumor protein levels of TOP2A and MIB-1 and ERG status with cancer-specific outcomes in men with high-risk prostate cancer treated by radical prostatectomy (RP). A 150-pair case-control study was designed from RP patients who developed systemic progression (SP) within 6 years of RP (cases) and men who were free of disease at least 8 years after RP (controls). The cases and controls were matched on conventional prognostic clinical… CONTINUE READING
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