The a , b , g , q-Unsaturated Aldehyde 2-trans-4-trans-Decadienal Disturbs DNA Replication and Mitotic Events in Early Sea Urchin Embryos

@inproceedings{Hansen2004TheA,
  title={The a , b , g , q-Unsaturated Aldehyde 2-trans-4-trans-Decadienal Disturbs DNA Replication and Mitotic Events in Early Sea Urchin Embryos},
  author={Espen Hansen and Yasmine Even and Anne-Marie Genevi{\`e}re},
  year={2004}
}
The polyunsaturated aldehydes are highly reactive products of fatty acid peroxidation and combustion of organic materials, and theyhavebeendocumented tohavediverse cyctotoxic andgenotoxic effects. The a,b,g,d-unsaturated aldehyde 2-trans-4-trans-decadienal is produced bymarinemicroalgae, and it is known to inhibit cell proliferation and induce apoptosis in several different cell types. However, the molecular basis for the cell cycle arrest is not fully understood.Weusedseaurchinembryos… CONTINUE READING
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