The Zuker collection: a resource for the analysis of autosomal gene function in Drosophila melanogaster.

@article{Koundakjian2004TheZC,
  title={The Zuker collection: a resource for the analysis of autosomal gene function in Drosophila melanogaster.},
  author={Edmund J Koundakjian and David S M Cowan and Robert W Hardy and Ann Becker},
  journal={Genetics},
  year={2004},
  volume={167 1},
  pages={203-6}
}
The majority of genes of multicellular organisms encode proteins with functions that are not required for viability but contribute to important physiological functions such as behavior and reproduction. It is estimated that 75% of the genes of Drosophila melanogaster are nonessential. Here we report on a strategy used to establish a large collection of stocks that is suitable for the recovery of mutations in such genes. From approximately 72,000 F(3) cultures segregating for autosomes heavily… CONTINUE READING
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