The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations.

@article{Meeth2016TheYL,
  title={The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations.},
  author={Katrina M Meeth and Jake Xiao Wang and Goran Micevic and William Damsky and Marcus W. Bosenberg},
  journal={Pigment cell & melanoma research},
  year={2016},
  volume={29 5},
  pages={
          590-7
        }
}
The remarkable success of immune therapies emphasizes the need for immune-competent cancer models. Elegant genetically engineered mouse models of a variety of cancers have been established, but their effective use is limited by cost and difficulties in rapidly generating experimental data. Some mouse cancer cell lines are transplantable to immunocompetent host mice and have been utilized extensively to study cancer immunology. Here, we describe the Yale University Mouse Melanoma (YUMM) lines, a… CONTINUE READING
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