The Y* rearrangement in mice: new insights into a perplexing PAR.

  title={The Y* rearrangement in mice: new insights into a perplexing PAR.},
  author={Paul S. Burgoyne and Shantha K Mahadevaiah and Jo E. Perry and Stephen J. Palmer and Alan Ashworth},
  journal={Cytogenetics and cell genetics},
  volume={80 1-4},
In essence, the Y* rearrangement in the mouse is a Y chromosome that has been hijacked by a non-Y centromere attached distal to the pseudoautosomal region (PAR). All the Y-unique material is thought to be unaltered, but the recombinatory behaviour of the Y* with the X during male meioisis led to the conclusion that part of the PAR is inverted. In the course of a cross set up to introduce the X-linked mutation Patchy fur (Paf) into XY* males, the Y* chromosome was found to carry the wild type… CONTINUE READING
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