The Xenopus homologue of Bicaudal-C is a localized maternal mRNA that can induce endoderm formation.

  • Ola Wessely, E M De Robertis
  • Published 2000 in Development


In Xenopus, zygotic transcription starts 6 hours after fertilization at the midblastula transition and therefore the first steps in embryonic development are regulated by maternally inherited proteins and mRNAs. While animal-vegetal polarity is already present in the oocyte, the dorsoventral axis is only established upon fertilization by the entry of the… (More)


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