The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells

@inproceedings{Crozat2010TheXC,
  title={The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells},
  author={Karine Crozat and Rachel Guiton and Vanessa Contreras and Vincent Feuillet and C A Dutertre and Erwan Ventre and Thien-Phong Vu Manh and Thomas Baranek and Anne Kristine Storset and Jacqueline Marvel and Pierre Boudinot and Anne Hosmalin and Isabelle Schwartz-Cornil and Marc Dalod},
  booktitle={The Journal of experimental medicine},
  year={2010}
}
Human BDCA3+ dendritic cells (DCs) were suggested to be homologous to mouse CD8alpha+ DCs. We demonstrate that human BDCA3+ DCs are more efficient than their BDCA1+ counterparts or plasmacytoid DCs (pDCs) in cross-presenting antigen and activating CD8+ T cells, which is similar to mouse CD8alpha+ DCs as compared with CD11b+ DCs or pDCs, although with more moderate differences between human DC subsets. Yet, no specific marker was known to be shared between homologous DC subsets across species… CONTINUE READING
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