The Working Memory Networks of the Human Brain

@article{Linden2007TheWM,
  title={The Working Memory Networks of the Human Brain},
  author={David E. J. Linden},
  journal={The Neuroscientist},
  year={2007},
  volume={13},
  pages={257 - 267}
}
  • D. Linden
  • Published 2007
  • Psychology, Medicine
  • The Neuroscientist
Working memory and short-term memory are closely related in their cognitive architecture, capacity limitations, and functional neuroanatomy, which only partly overlap with those of long-term memory. The author reviews the functional neuroimaging literature on the commonalities and differences between working memory and short-term memory and the interplay of areas with modality-specific and supramodal representations in the brain networks supporting these fundamental cognitive processes. Sensory… Expand
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References

SHOWING 1-10 OF 62 REFERENCES
Transient and sustained activity in a distributed neural system for human working memory
TLDR
Using fMRI to obtain dynamic measures of neural activity related to different components of a face working memory task, a continuum of functional specialization is revealed, from occipital through multiple prefrontal areas, regarding each area's relative contribution to perceptual and mnemonic processing. Expand
Content- and Task-Specific Dissociations of Frontal Activity during Maintenance and Manipulation in Visual Working Memory
TLDR
It is suggested that the enhanced demand on cognitive resources in manipulation compared with maintenance was met by interplay of content- and task-specific modules in a frontoparietal network. Expand
Cortical capacity constraints for visual working memory: dissociation of fMRI load effects in a fronto-parietal network
TLDR
Results indicate that at least two distinct cortical subsystems are recruited for visual WM, and that their interplay changes when the capacity limit is reached. Expand
Neuroanatomic Overlap of Working Memory and Spatial Attention Networks: A Functional MRI Comparison within Subjects
TLDR
The use of two different tasks in the same set of subjects allowed us to provide an unequivocal demonstration that the neural networks subserving spatial attention and working memory intersect at several frontoparietal sites, and support the view that major cognitive domains are represented by partially overlapping large-scale neural networks. Expand
Redefining the functional organization of working memory processes within human lateral prefrontal cortex
TLDR
PET dissociation provides unambiguous evidence that the mid‐dorsolateral and mid‐ventrolateral frontal cortical areas make distinct functional contributions to spatial working memory and corresponds with a fractionation of working memory processes in psychological terms. Expand
Seeking the Neural Substrates of Visual Working Memory Storage
TLDR
The results suggest that no part of frontal cortex, including PFC, stores mnemonic representation of faces reliably across distracted delay periods, and working memory storage of faces is mediated by a domain-specific network in posterior cortex. Expand
Segregation of areas related to visual working memory in the prefrontal cortex revealed by rTMS.
TLDR
RTMS is applied to transiently and selectively disrupt the function of the dorsomedial, dorsolateral or ventral prefrontal cortex in normal human volunteers performing either a spatial or a face-recognition delayed-response task, providing evidence of domain-specific segregation of WM functions in widely separated areas of prefrontal cortex. Expand
Distributed cortical systems in visual short-term memory revealed by event-related functional magnetic resonance imaging.
TLDR
This work investigated visual short-term memory for objects, places and conjunctions in humans using event-related time-resolved functional magnetic resonance imaging that permitted segregation of encoding, retention and retrieval phases and confirmed a posterior-anterior and right-left dissociation for spatial versus non-spatial memory. Expand
Neural system for controlling the contents of object working memory in humans.
Working memory (WM), the active maintenance of currently relevant information, is a flexible system allowing for fast and frequent goal-directed changes of rehearsed information. Successful WMExpand
Dissociable functional cortical topographies for working memory maintenance of voice identity and location.
TLDR
Functional magnetic resonance imaging and a single set of auditory stimuli suggest that, during auditory working memory, maintenance of spatial and nonspatial information modulates activity preferentially in a dorsal and a ventral auditory pathway, respectively. Expand
...
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