The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development.

Abstract

The vertebrate embryonic vasculature develops from angioblasts, which are specified from mesodermal precursors and develop in close association with blood cells. The signals that regulate embryonic vasculogenesis and angiogenesis are incompletely understood. Here, we show that R-spondin 3 (Rspo3), a member of a novel family of secreted proteins in… (More)
DOI: 10.1242/dev.027284

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Cite this paper

@article{Kazanskaya2008TheWS, title={The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development.}, author={Olga V. Kazanskaya and Bisei Ohkawara and M{\'e}lanie H{\'e}roult and Wei Wu and Nicole Maltry and Hellmut G Augustin and Christof Niehrs}, journal={Development}, year={2008}, volume={135 22}, pages={3655-64} }