The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

Abstract

Malignant astrocytomas are highly aggressive brain tumours with poor prognosis. While a number of structural genomic changes and dysregulation of signalling pathways in gliomas have been described, the identification of biomarkers and druggable targets remains an important task for novel diagnostic and therapeutic approaches. Here, we show that the Wnt… (More)
DOI: 10.1002/emmm.201100186

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