The Wiedemann-Beckwith syndrome: pedigree studies on five families with evidence for autosomal dominant inheritance with variable expressivity.

Abstract

We describe 18 individuals from five unrelated families with various manifestations of the Wiedemann-Beckwith syndrome. Pedigree analysis was performed on the 5 families and on another 19 families in the literature, each of which included more than one affected person. The following findings were obtained: 1) the clinical manifestations among the affected… (More)

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@article{Niikawa1986TheWS, title={The Wiedemann-Beckwith syndrome: pedigree studies on five families with evidence for autosomal dominant inheritance with variable expressivity.}, author={Norrio Niikawa and Satoshi Ishikiriyama and S. Takahashi and Arinori Inagawa and Haruka Tonoki and Y. Ohta and N. Hase and Toshiaki Kamei and Tadashi Kajii}, journal={American journal of medical genetics}, year={1986}, volume={24 1}, pages={41-55} }