The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.

@article{Menndez2013TheWE,
  title={The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.},
  author={Javier A. Men{\'e}ndez and Jorge Joven and S{\'i}lvia Cuf{\'i} and Bruna Corominas-Faja and Cristina Oliveras-Ferraros and Elisabet Cuy{\`a}s and Bego{\~n}a Mart{\'i}n-Castillo and Eugeni L{\'o}pez-Bonet and Tom{\'a}s Alarc{\'o}n and Alejandro V{\'a}zquez-Mart{\'i}n},
  journal={Cell cycle},
  year={2013},
  volume={12 8},
  pages={1166-79}
}
When fighting cancer, knowledge on metabolism has always been important. Today, it matters more than ever. The restricted cataloging of cancer genomes is quite unlikely to achieve the task of curing cancer, unless it is integrated into metabolic networks that respond to and influence the constantly evolving cancer stem cell (CSC) cellular states. Once the genomic era of carcinogenesis had pushed the 1920s Otto Warburg's metabolic cancer hypothesis into obscurity for decades, the most recent… CONTINUE READING
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