The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells

@inproceedings{Wang2018TheWE,
  title={The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells},
  author={Feng Wang and Hongyi Liu and Lijuan Hu and Yunfei Liu and Yijie Duan and Rui Cui and Wencong Tian},
  booktitle={BMC Cancer},
  year={2018}
}
Cancer cachexia is a cancer-induced metabolic disorder and a major cause of cancer-induced death. The constituents of cancer cachexia include an increase in energy expenditure, hepatic gluconeogenesis, fat lipolysis, and skeletal-muscle proteolysis and a decrease in body weight. The aetiology of cancer cachexia is unclear and may involve cancer-cell metabolism and secretion. In this study, we investigated whether the high glycolysis in cancer cells (the Warburg effect) triggers cachexia in… CONTINUE READING
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