The Vulnerable Ventral Tegmental Area in Parkinson's Disease.

  title={The Vulnerable Ventral Tegmental Area in Parkinson's Disease.},
  author={Stephanie Lorraine Alberico and Martin D. Cassell and Nandakumar S. Narayanan},
  journal={Basal ganglia},
  volume={5 2-3},
INTRODUCTION The involvement of dopaminergic neurons in the ventral tegmental area (VTA) in Parkinson's disease (PD) has not been universally recognized by neuroscientists and neurologists. Here, we conduct a review of previous research documenting dopaminergic neuronal loss in both the substantia nigra pars compacta (SNpc) and VTA and add three new post-mortem PD cases to the literature. METHODS PD and control brains were sectioned, stained for tyrosine hydroxylase, and cells in the SNpc and… CONTINUE READING
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