The Vitamin D requirement in health and disease

@article{Heaney2005TheVD,
  title={The Vitamin D requirement in health and disease},
  author={Robert P. Heaney},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2005},
  volume={97},
  pages={13-19}
}
Advances in Vitamin D nutritional physiology since publication of the DRIs in 1997 are briefly summarized. Available data indicate that (1) Vitamin D's canonical function, optimizing intestinal calcium absorption, is fully expressed at serum 25-hydroxyvitamin D (25OHD) concentration of approximately 80nmol/L; (2) elevated parathyroid activity, typical of aging populations, is minimized at the same 25OHD value and (3) osteoporotic fractures are reduced when serum 25OHD is raised to near 80nmol/L… CONTINUE READING

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