• Corpus ID: 58913253

The Vital Consequences of Choosing the Right UV-filter for the Prevention of Free Radical Boosting in UV-irradiated Skin after the Application of Self Tanning Creams: Part 2

@inproceedings{Jung2008TheVC,
  title={The Vital Consequences of Choosing the Right UV-filter for the Prevention of Free Radical Boosting in UV-irradiated Skin after the Application of Self Tanning Creams: Part 2},
  author={Katinka Jung and Simon Champ and H. Fl{\"o}sser-M{\"u}ller and M. Seifert and Th. Herrling},
  year={2008}
}

• K. Jung, S. Champ, +2 authors T. Herrling
• Published 2008
• Medicine

It is generally known that the Maillard reaction which is responsible for the sunless tanning is correlated with the generation of free radicals in the skin. The number of free radicals is dramatically increased by simultaneous UV exposure and results in a strong decrease of the Radical Skin Protection Factor of RSF “1.0. This decrease of the RSF is correlated with a reduction of the self protection time of the skin. A waiting time between DHA application and the beginning of the sun irradiation can prevent this boosting effect of free radicals and leads to normal RSF values of unprotected skin of RSF=1.0. The general aim of this study was the prevention of the dramatic increase of generated free radicals in skin rather than the elimination of these free radicals by free radical scavengers like antioxidants. That's why this study concerns oneself with the application of DHA crerams containing UV filters resulting in values of RSF> 1.0. Four filters : two UVB filters, one UVA filter and a UVA filter were tested corresponding to their protection against DHA induced and UV boosted free radicals in skin. The radical protection realized by these UV filters extends over a wide range corresponding to the concentration and residence time of DHA inclusive the used UV dose. RSF values from RSF 0.56 for the application of a UVB filter with a residence tome of 20 min at 2 MED up to an RSF=1.8 for a UVA filter were measured under the same conditions. The prolongation of the time between DHA application and sun exposure at 4 hours resulted in a further increase of the radical protection factor onto an RSF=24.3. The determination of the waiting time inclusive of the radical protection factor are essential parameters characterizing self tanning creams.