The Viral Origins of Telomeres and Telomerases and their Important Role in Eukaryogenesis and Genome Maintenance

@article{Witzany2008TheVO,
  title={The Viral Origins of Telomeres and Telomerases and their Important Role in Eukaryogenesis and Genome Maintenance},
  author={Guenther Witzany},
  journal={Biosemiotics},
  year={2008},
  volume={1},
  pages={191-206}
}
Whereas telomeres protect terminal ends of linear chromosomes, telomerases identify natural chromosome ends, which differ from broken DNA and replicate telomeres. Although telomeres play a crucial role in the linear chromosome organization of eukaryotic cells, their molecular syntax most probably descended from an ancient retroviral competence. This indicates an early retroviral colonization of large double-stranded DNA viruses, which are putative ancestors of the eukaryotic nucleus. This… 
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