The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters

@article{Pompeani2008TheVH,
  title={The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters},
  author={Audra J. Pompeani and Joseph Irgon and Michael F. Berger and Martha L. Bulyk and Ned S. Wingreen and Bonnie L Bassler},
  journal={Molecular Microbiology},
  year={2008},
  volume={70},
  pages={76 - 88}
}
Quorum sensing is the process of cell-to-cell communication by which bacteria communicate via secreted signal molecules called autoinducers. As cell population density increases, the accumulation of autoinducers leads to co-ordinated changes in gene expression across the bacterial community. The marine bacterium, Vibrio harveyi, uses three autoinducers to achieve intra-species, intra-genera and inter-species cell-cell communication. The detection of these autoinducers ultimately leads to the… CONTINUE READING