The Vibrio cholerae Cytolysin Promotes Chloride Secretion from Intact Human Intestinal Mucosa

@article{Debellis2009TheVC,
  title={The Vibrio cholerae Cytolysin Promotes Chloride Secretion from Intact Human Intestinal Mucosa},
  author={Lucantonio Debellis and Anna Diana and Diletta Arcidiacono and Romina Fiorotto and Piero Portincasa and D F Altomare and Carlo Spirl{\'i} and Marina de Bernard},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={117 - 124}
}
BACKGROUND The pathogenicity of the Vibrio cholerae strains belonging to serogroup O1 and O139 is due to the production of virulence factors such as cholera toxin (CT) and the toxin-coregulated pilus (TCP). The remaining serogroups, which mostly lack CT and TCP, are more frequently isolated from aquatic environmental sources than from clinical samples; nevertheless, these strains have been reported to cause human disease, such as sporadic outbreaks of watery diarrhoea and inflammatory… CONTINUE READING
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