The Ventral Pallidum is Critically Involved in the Development and Expression of Morphine-Induced Sensitization

@article{Mickiewicz2009TheVP,
  title={The Ventral Pallidum is Critically Involved in the Development and Expression of Morphine-Induced Sensitization},
  author={Amanda L. Mickiewicz and Jeanine E Dallimore and T. Celeste Napier},
  journal={Neuropsychopharmacology},
  year={2009},
  volume={34},
  pages={874-886}
}
Repeated, intermittent exposure to drugs of abuse results in response enhancements to subsequent drug treatments, a phenomenon referred to as sensitization. As persistent neuronal sensitization may contribute to the long-lasting consequences of drug abuse, characterizing the neuroanatomical substrates of sensitization is providing insights into addiction. It is known that the ventral tegmental area (VTA) is necessary for induction, and expression involves the nucleus accumbens (NAc). We reveal… CONTINUE READING