The Validity of Left Ventricular Mass as a Surrogate End Point for All-Cause and Cardiovascular Mortality Outcomes in People With CKD: A Systematic Review and Meta-analysis.

@article{Badve2016TheVO,
  title={The Validity of Left Ventricular Mass as a Surrogate End Point for All-Cause and Cardiovascular Mortality Outcomes in People With CKD: A Systematic Review and Meta-analysis.},
  author={Sunil V. Badve and Suetonia C Palmer and Giovanni F M Strippoli and Matthew A Roberts and Armando Teixeira-Pinto and Neil C Boudville and Alan Cass and Carmel Mary Hawley and Swapnil Hiremath and Elaine M Pascoe and Vlado Perkovic and Gillian A Whalley and Jonathan C Craig and David W Johnson},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2016},
  volume={68 4},
  pages={554-563}
}
BACKGROUND Left ventricular mass (LVM) is a widely used surrogate end point in randomized trials involving people with chronic kidney disease (CKD) because treatment-induced LVM reductions are assumed to lower cardiovascular risk. The aim of this study was to assess the validity of LVM as a surrogate end point for all-cause and cardiovascular mortality in CKD. STUDY DESIGN Systematic review and meta-analysis. SETTING & POPULATION Participants with any stages of CKD. SELECTION CRITERIA FOR… CONTINUE READING
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