The Validation of a Functional, Isolated Pig Bladder Model for Physiological Experimentation

@inproceedings{Parsons2012TheVO,
  title={The Validation of a Functional, Isolated Pig Bladder Model for Physiological Experimentation},
  author={Brian Andrew Parsons and Marcus J Drake and Andrew Gammie and Christopher Henry Fry and Bahareh Vahabi},
  booktitle={Front. Pharmacol.},
  year={2012}
}
Characterizing the integrative physiology of the bladder requires whole organ preparations. The purpose of this study was to validate an isolated large animal (pig) bladder preparation, through arterial and intravesical drug administration, intravesical pressure recording, and filming of surface micromotions. Female pig bladders were obtained from the local abattoir and arterially perfused in vitro. Arterial and intravesical pressures were recorded at varying volumes. Bladder viability was… CONTINUE READING
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