The Validation of a Functional, Isolated Pig Bladder Model for Physiological Experimentation

  title={The Validation of a Functional, Isolated Pig Bladder Model for Physiological Experimentation},
  author={Brian Andrew Parsons and Marcus J Drake and Andrew Gammie and Christopher Henry Fry and Bahareh Vahabi},
  booktitle={Front. Pharmacol.},
Characterizing the integrative physiology of the bladder requires whole organ preparations. The purpose of this study was to validate an isolated large animal (pig) bladder preparation, through arterial and intravesical drug administration, intravesical pressure recording, and filming of surface micromotions. Female pig bladders were obtained from the local abattoir and arterially perfused in vitro. Arterial and intravesical pressures were recorded at varying volumes. Bladder viability was… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 36 references

The role of a leaky urothelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive

  • C. L. Parsons
  • 2011
2 Excerpts

Differential effect of L-cysteine in isolated whole-bladder preparations

  • H. S. Buyuknacar, C. Gocmen, W. C. De Groat, E. K. Kumcu, H. Y. Wu, S. Onder
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…