The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.

Abstract

Brain-derived neurotrophic-factor (BDNF), the most abundant of the neurotrophins in the brain, has been implicated in both major depression and cognitive function. This study examines the association between the BDNF-gene Val66Met polymorphism and depression susceptibility and severity, age-of-onset, cognitive function and suicidal attempt history in an… (More)

Topics

Cite this paper

@article{Hwang2006TheVP, title={The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.}, author={Jen-Ping Hwang and Shih-Jen Tsai and C J Hong and Chen-Hong Yang and Jiing-Feng Lirng and Ya-min Yang}, journal={Neurobiology of aging}, year={2006}, volume={27 12}, pages={1834-7} }