• DOI:10.1016/j.neurobiolaging.2005.10.013
Corpus ID: 23626890

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression

@article{Hwang2006TheVP,
  title={The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression},
  author={Jen-Ping Hwang and S. Tsai and Chen-Jee Hong and Chen-Hong Yang and Yamin Yang},
  journal={Neurobiology of Aging},
  year={2006},
  volume={27},
  pages={1834-1837}
}

Jen-Ping Hwang, S. Tsai, +2 authors Yamin Yang

Published 2006

Psychology, Medicine

Neurobiology of Aging

Brain-derived neurotrophic-factor (BDNF), the most abundant of the neurotrophins in the brain, has been implicated in both major depression and cognitive function. This study examines the association between the BDNF-gene Val66Met polymorphism and depression susceptibility and severity, age-of-onset, cognitive function and suicidal attempt history in an elderly Chinese sample population. We genotyped the BDNF-gene Val66Met polymorphism in 110 elderly inpatients diagnosed with major depression… CONTINUE READING

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