The UspA2 protein of Moraxella catarrhalis is directly involved in the expression of serum resistance.

@article{Attia2005TheUP,
  title={The UspA2 protein of Moraxella catarrhalis is directly involved in the expression of serum resistance.},
  author={Ahmed S Attia and Eric R. Lafontaine and J. L. Latimer and Christoph Aebi and George A. Syrogiannopoulos and Eric J. Hansen},
  journal={Infection and immunity},
  year={2005},
  volume={73 4},
  pages={2400-10}
}
Many strains of Moraxella catarrhalis are resistant to the bactericidal activity of normal human serum. Previous studies have shown that mutations involving the insertion of an antibiotic resistance cartridge into the M. catarrhalis uspA2 gene resulted in the conversion of a serum-resistant strain to a serum-sensitive phenotype. In the present study, the deletion of the entire uspA2 gene from the serum-resistant M. catarrhalis strain O35E resulted in a serum-sensitive phenotype and did not… CONTINUE READING
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