The Use of Three Long Non-Coding RNAs as Potential Prognostic Indicators of Astrocytoma

@inproceedings{Zhi2015TheUO,
  title={The Use of Three Long Non-Coding RNAs as Potential Prognostic Indicators of Astrocytoma},
  author={Feng Zhi and Qiang Wang and Lian Bi Xue and Naiyuan Shao and Rong Wang and Danni Deng and Suinuan Wang and Xiwei Xia and Yilin Yang and Vinod Scaria},
  booktitle={PloS one},
  year={2015}
}
Long noncoding RNAs (lncRNAs) are pervasively transcribed and play a key role in tumorigenesis. The aim of the study was to determine the lncRNA expression profile in astrocytomas and to assess its potential clinical value. We performed a three-step analysis to establish the lncRNA profile for astrocytoma: a) the lncRNA expression was examined on 3 astrocytomas as well as 3 NATs (normal adjacent tissues) using the lncRNA microarray; b) the top-hits were validated in 40 astrocytomas (WHO grade… CONTINUE READING
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