• Corpus ID: 13578359

The Use of Medium-Chain Triglycerides in Gastrointestinal Disorders

@inproceedings{Shah2017TheUO,
  title={The Use of Medium-Chain Triglycerides in Gastrointestinal Disorders},
  author={Neha Shah},
  year={2017}
}
INTRODUCTION Medium-chain triglycerides (MCTs) comprise a glycerol molecule attached to 3 fatty acid chains ranging between 6 to 12 carbons in length. Unlike most other lipid molecules that require a complex process of digestion, MCTs are more easily absorbed into the bloodstream from the gastrointestinal tract. These features of MCTs confer unique benefits in the management of gastrointestinal disorders.1 As such, MCTs have historically been used to treat steatorrhea resulting from… 
med.virginia.edu
44 Citations
Background Citations
17
Methods Citations
2

Tables from this paper

44 Citations

Citation Type

Citation Type

Medium-chain fatty acids in nutritional therapy: A review
TLDR
The current review highlights the nutritional impacts of MCFA and its utilization in disease therapy and suggests that ketone bodies have been suggested to produce larger amounts of energy compared to glucose.
Medium chain triglycerides (MCT): State-of-the-art on chemistry, synthesis, health benefits and applications in food industry.
Medium chain triglycerides (MCT) are esters of fatty acids with 6 to 12 carbon atom chains. Naturally, they occur in various sources; their composition and bioactivity are source and extraction…
Reviews of medium- and long-chain triglyceride with respect to nutritional benefits and digestion and absorption behavior.
Effect of medium chain fatty acid in human health and disease
Optimization of Hydrocolloid Levels in Medium-Chain Triglyceride-Enriched Soymilk by Response Surface Methodology
The application of medium-chain triglycerides (MCT) in food items can pave the way for its increased utilization and for consumers to avail of its benefits. Preliminary studies have indicated that…
Effects of medium chain triglycerides with organic acids on growth performance, fecal score, blood profiles, intestinal morphology, and nutrient digestibility in weaning pigs
Objective This study was conducted to evaluate the effects of medium chain triglycerides (MCT) with organic acids (OA) on growth performance, fecal score, blood profiles, intestinal morphology, and…
Fatty Acid Diets: Regulation of Gut Microbiota Composition and Obesity and Its Related Metabolic Dysbiosis
TLDR
The type of fatty acids and their amount are discussed, including the administration time and their interplay with gut microbiota and its results about health or several metabolic dysbioses undergone by hosts.
Enteral Nutrition Formulas: Current Evidence and Nutritional Composition
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice
TLDR
A role for Sirt5 is revealed in regulating the hepatic response to MCT and light is shed into the pathogenesis of periportal macrovesicular steatosis, a hallmark of human pediatric non-alcoholic fatty liver disease.
Physicochemical properties and volatile formation mechanism of medium-chain triacylglycerols during heating.
Medium-chain triacylglycerols (MCTs), including caprylic acid (C8), a mixture of caprylic acid and capric acid (C8+C10), and high-MCT coconut oil (HMCO), were heated at 180°C. Their volatile profiles…
...
...

References

SHOWING 1-10 OF 21 REFERENCES
Medium-chain triglycerides: an update.
A review of the literature on the medical and nutritional use of medium-chain triglycerides (MCTs) since 1970 is presented with additional discussions on the various modifications and applications of…
The effect of equicaloric medium‐chain and long‐chain triglycerides on pancreas enzyme secretion
TLDR
It is concluded that enteral administration of MCT in the proximal jejunum does not stimulate exocrine pancreatic secretion nor gallbladder contraction or CCK release, in contrast to an equicaloric amount of LCT.
Medium chain triglycerides and structured lipids
TLDR
In the search for alternative noncarbohydrate fuels, medium chain triglycerides (MCT) are unique and have established themselves in the areas of malabsorption syndrome cases and infant care and as a high energy, rapidly available fuel.
The influence of a preserved colon on the absorption of medium chain fat in patients with small bowel resection
TLDR
In small bowel resected patients, the colon seems to serve as a digestive organ for medium chain fat, probably absorbed as MCFAs, perhaps because like the SCFAs they are water soluble.
Comparison of effects of ingested mediumand long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides
TLDR
The long-chain triglyceride meal evoked a brisk and sustained gallbladder contraction, higher levels of CCK, and a significant increase in plasma PP and GIP levels.
An Enteral Therapy Containing Medium-Chain Triglycerides and Hydrolyzed Peptides Reduces Postprandial Pain Associated with Chronic Pancreatitis
TLDR
A complete enteral supplement containing MCT and hydrolyzed peptides minimally increases plasma CCK levels and may be effective in reducing postprandial pain associated with chronic pancreatitis.
Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications.
Enteral nutrition for patients with cystic fibrosis: comparison of a semi-elemental and nonelemental formula.
Thermogenesis in humans during overfeeding with medium-chain triglycerides.
Advanced Nutrition and Human Metabolism
TLDR
The Cell: A Microcosm of Life and the Digestive System: Mechanisms for Nourishing the body and the Impact of Exercise and Sport are presented.
...
...