The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms: To the Editor.

@article{Ribeiro2016TheUO,
  title={The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms: To the Editor.},
  author={Carolina Medeiros da Frota Ribeiro and Gerard S Sanacora and Ralph Hoffman and Robert Ostroff},
  journal={Biological psychiatry},
  year={2016},
  volume={79 9},
  pages={e65-6}
}
Mounting evidence from a series of small clinical trials and case series suggests ketamine can have rapid and robust antidepressant (1) and possibly antisuicidal effects (2) in patients who did not respond to standard treatment options. However, because of the variable psychotomimetic effects of ketamine in healthy volunteers and exacerbation of previously experienced positive symptoms in schizophrenic volunteers (3,4), patients previously experiencing psychotic features have been excluded from… CONTINUE READING
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