The Use of Corticosteroids to Treat Keloids: A Review

@article{Roques2008TheUO,
  title={The Use of Corticosteroids to Treat Keloids: A Review},
  author={Claude Roques and Luc T{\'e}ot},
  journal={The International Journal of Lower Extremity Wounds},
  year={2008},
  volume={7},
  pages={137 - 145}
}
  • C. Roques, L. Téot
  • Published 1 September 2008
  • Medicine
  • The International Journal of Lower Extremity Wounds
Mechanisms for keloid formation include drastic changes in growth factor actions, collagen turnover, mechanical forces applied over the skin, and genetic and immunologic contributions. The use of corticosteroids to manage keloids increases basic fibroblast growth factor production while decreasing transforming growth factor-β1 production by human dermal fibroblasts, endogenous vascular endothelial growth factor, and insulin-like growth factor-1. The use of corticosteroid injections is, to date… 
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  • F. Syed, A. Bayat
  • Medicine, Biology
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
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This is the first study to report the efficacy of three well‐known steroids on KF and suggest that combination may be superior than using a single steroid in treating KD.
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