The Use of Antidotes for Calcium Gluconate Extravasation: An Experimental Study in Mice.

@article{Compaa2018TheUO,
  title={The Use of Antidotes for Calcium Gluconate Extravasation: An Experimental Study in Mice.},
  author={Francisco Javier Pacheco Compa{\~n}a and Jos{\'e} Mid{\'o}n M{\'i}guez and Francisco Javier de Toro Santos and Alberto Centeno Cort{\'e}s and Patricia L{\'o}pez San Mart{\'i}n and Mar{\'i}a Teresa Yebra-Pimentel Vidal and Joaqu{\'i}n Jos{\'e} Mosquera Os{\'e}s},
  journal={Plastic and reconstructive surgery},
  year={2018},
  volume={142 3},
  pages={
          699-707
        }
}
BACKGROUND Calcium gluconate extravasation is a process that can cause serious lesions, such as necrosis and calcification of the soft tissues. The aim of the present study was to analyze the beneficial effects of four possible local antidotes for calcium gluconate extravasation: hyaluronidase, sodium thiosulfate, triamcinolone acetonide, and physiologic saline solution. METHODS Seventy-four BALB/c mice were used in the study. The substances selected for use in this study were calcium… CONTINUE READING
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