The Use Of A Calcium‐Channel Blocker, Nicardipine, For Severely Asphyxiated Newborn Infants

@article{Levene1990TheUO,
  title={The Use Of A Calcium‐Channel Blocker, Nicardipine, For Severely Asphyxiated Newborn Infants},
  author={Malcolm I. Levene and Neil A. Gibson and Alan Charles Fenton and E. Papathoma and David B. Barnett},
  journal={Developmental Medicine \& Child Neurology},
  year={1990},
  volume={32}
}
A continuous infusion of nicardipine was given to four severely asphyxiated fullterm infants who were at high risk for adverse outcome and had abnormal cerebral Doppler haemodynamic studies. The heart rate increased in all four infants and mean arterial blood pressure (MAP) fell in three. Two infants had a sudden and marked fall in MAP, together with severe impairment of skin blood‐flow and a concurrent fall in cerebral blood‐flow velocity. The serum level of nicardipine was <40ng/mL in all… 
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