The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein.

@article{Yang2015TheUP,
  title={The Us3 Protein of Herpes Simplex Virus 1 Inhibits T Cell Signaling by Confining Linker for Activation of T Cells (LAT) Activation via TRAF6 Protein.},
  author={Yin Yang and Songfang Wu and Yong Wang and Shuang Pan and Bei Lan and Yaohui Liu and Liming Zhang and Qianli Leng and Da Chen and Cui-zhu Zhang and Bin He and Youjia Cao},
  journal={The Journal of biological chemistry},
  year={2015},
  volume={290 25},
  pages={15670-8}
}
Herpes simplex virus 1 (HSV-1) is the most prevalent human virus and causes global morbidity because the virus is able to infect multiple cell types. Remarkably, HSV infection switches between lytic and latent cycles, where T cells play a critical role. However, the precise way of virus-host interactions is incompletely understood. Here we report that HSV-1… CONTINUE READING