The Ups and Downs of Motion Sickness

@article{Herron2010TheUA,
  title={The Ups and Downs of Motion Sickness},
  author={Dorothy G Herron},
  journal={AJN, American Journal of Nursing},
  year={2010},
  volume={110},
  pages={49-51}
}
  • Dorothy G Herron
  • Published 1 December 2010
  • Psychology, Medicine
  • AJN, American Journal of Nursing
Overview: Nearly everyone will experience motion sickness at some point. It's thought to be caused by confusion among the vestibular, visual, and proprioceptive systems; the associated nausea is thought to involve neurons in the hypothalamus and a portion of the cerebral cortex. Although many remedies are available, none has been proven to be effective for everyone. Pharma cologic treatments include antihistamines, scopolamine, and gingerroot. Nonpharmacologic treatments include efforts to… 
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References

SHOWING 1-10 OF 24 REFERENCES
Physiological basis and pharmacology of motion sickness: an update
TLDR
Effective drugs for combating motion sickness include antihistamines, antimuscarinics, 5-HT1A (serotonergic) receptor agonists and neurokinin type 1 receptor antagonists, but considerable information concerning the physiological basis and pharmacology of motion sickness is unknown.
Motion sickness may be caused by a neurohumoral action of acetylcholine.
TLDR
A new hypothesis is herein presented which posits that acetylcholine (ACh) acts as a neurohumeral agent to bring about the symptoms associated with motion sickness.
Scopolamine (hyoscine) for preventing and treating motion sickness.
TLDR
Assessment of the effectiveness of scopolamine versus no therapy, placebo, other drugs, behavioural and complementary therapy or two or more of the above therapies in combination for motion sickness in persons (both adults and children) without known vestibular, visual or central nervous system pathology found it more effective than placebo in the prevention of symptoms.
MOTION SICKNESS, GINGER, AND PSYCHOPHYSICS
Abstract The effects of the powdered rhizome of Zingiber officinale on the symptoms of motion sickness were compared with those of dimenhydrinate and placebo in 36 undergraduate men and women who
Effect of seating, vision and direction of horizontal oscillation on motion sickness.
TLDR
In the conditions of the experiment the effects of the postural support given to the subjects and their prior susceptibility to motion sickness were greater than any effect of the visual conditions.
Autogenic‐Feedback Training Exercise Is Superior to Promethazine for Control of Motion Sickness Symptoms
TLDR
The AFTE group showed significantly less heart rate and skin conductance variability during motion sickness tests administered after training, and the primary physiological effect of promethazine was an inhibition of skin Conductance level.
Chlorpheniramine for motion sickness.
TLDR
Chlorpheniramine is effective and could be considered for use against motion sickness, and has the potential to be administered transdermally.
Effects of dimenhydrinate on gastric tachyarrhythmia and symptoms of vection-induced motion sickness.
TLDR
It is concluded that dimenhydrinate reduced motion sickness symptoms at least in part by depressing central nervous system activity and possibly by suppressing abnormal gastric myoelectric activity.
Motion sickness amelioration induced by prism spectacles
A side effect of the prescription of prism glasses according to the principle of Utermöhlen to improve mechanical reading skills of certain types of learning disabled children was the alleviation of
Slow deep breathing prevents the development of tachygastria and symptoms of motion sickness.
TLDR
In conclusion, slow deep breathing in a situation previously demonstrated to provoke tachygastria prevented the development of gastric dysrhythmias and decreased symptoms of motion sickness.
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