The Ups and Downs of Motion Sickness

  title={The Ups and Downs of Motion Sickness},
  author={Dorothy G Herron},
  journal={AJN, American Journal of Nursing},
  • Dorothy G Herron
  • Published 1 December 2010
  • Psychology, Medicine
  • AJN, American Journal of Nursing
Overview: Nearly everyone will experience motion sickness at some point. It's thought to be caused by confusion among the vestibular, visual, and proprioceptive systems; the associated nausea is thought to involve neurons in the hypothalamus and a portion of the cerebral cortex. Although many remedies are available, none has been proven to be effective for everyone. Pharma cologic treatments include antihistamines, scopolamine, and gingerroot. Nonpharmacologic treatments include efforts to… 
Motion sickness: an overview
In most cases, motion sickness can be prevented by behavioral and environmental modifications (avoidance, habituation, and minimization of motion stimuli).
Meclizine: Safety and Efficacy in the Treatment and Prevention of Motion Sickness
Meclizine is a piperzine antihistamine that is effective for the prevention and treatment of motion sickness, particularly during mild civilian travel.
Assessment of otolith function using cervical and ocular vestibular evoked myogenic potentials in individuals with motion sickness
Evaluating the otolith functioning in individuals with motion sickness revealed no significant difference in latencies and amplitudes between groups, but thresholds were significantly elevated and inter-aural asymmetry ratio significantly higher in motion sickness susceptible group.
Reduction of Motion Sickness Through Targeting Histamine N-Methyltransferase in the Dorsal Vagal Complex of the Brain
HnMT expression in the brain stem is inversely correlated with MS development, and increasing HNMT expression or stimulating its activity in the DVC could inhibit MS.
Experimental hydrops of labyrinth
Difficulties in approbation of drugs for the treatment of vestibular dysfunction are associated with a lack of knowledge of the mechanisms of its development. In particular, it is necessary to take
A Medical Food Formulation of Griffonia simplicifolia/Magnesium for Childhood Periodic Syndrome Therapy: An Open-Label Study on Motion Sickness.
The findings of the present study suggest the role of the Griffonia/magnesium complex as a potential treatment with middle-term efficacy even for MS.
Inner Ear Arginine Vasopressin-Vasopressin Receptor 2-Aquaporin 2 Signaling Pathway Is Involved in the Induction of Motion Sickness
It has been identified that arginine vasopressin (AVP), vasopressin receptor 2(V2R), and the aquaporin 2 (AQP2) signaling pathway in the inner ear play important roles in hearing and balance
Supporting Family Caregivers: Communicating with Family Caregivers
  • M. Walton
  • Medicine
    The American journal of nursing
  • 2011
Nurses can foster partnerships with patients and families during acute care hospitalizations and builds on the work addressed in AJN's September 2008 State of the Science report, "Professional Partners Supporting Family Caregivers".
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Physiological basis and pharmacology of motion sickness: an update
Effective drugs for combating motion sickness include antihistamines, antimuscarinics, 5-HT1A (serotonergic) receptor agonists and neurokinin type 1 receptor antagonists, but considerable information concerning the physiological basis and pharmacology of motion sickness is unknown.
Motion sickness may be caused by a neurohumoral action of acetylcholine.
A new hypothesis is herein presented which posits that acetylcholine (ACh) acts as a neurohumeral agent to bring about the symptoms associated with motion sickness.
Scopolamine (hyoscine) for preventing and treating motion sickness.
Assessment of the effectiveness of scopolamine versus no therapy, placebo, other drugs, behavioural and complementary therapy or two or more of the above therapies in combination for motion sickness in persons (both adults and children) without known vestibular, visual or central nervous system pathology found it more effective than placebo in the prevention of symptoms.
Abstract The effects of the powdered rhizome of Zingiber officinale on the symptoms of motion sickness were compared with those of dimenhydrinate and placebo in 36 undergraduate men and women who
Effect of seating, vision and direction of horizontal oscillation on motion sickness.
In the conditions of the experiment the effects of the postural support given to the subjects and their prior susceptibility to motion sickness were greater than any effect of the visual conditions.
Autogenic‐Feedback Training Exercise Is Superior to Promethazine for Control of Motion Sickness Symptoms
The AFTE group showed significantly less heart rate and skin conductance variability during motion sickness tests administered after training, and the primary physiological effect of promethazine was an inhibition of skin Conductance level.
Chlorpheniramine for motion sickness.
Chlorpheniramine is effective and could be considered for use against motion sickness, and has the potential to be administered transdermally.
Effects of dimenhydrinate on gastric tachyarrhythmia and symptoms of vection-induced motion sickness.
It is concluded that dimenhydrinate reduced motion sickness symptoms at least in part by depressing central nervous system activity and possibly by suppressing abnormal gastric myoelectric activity.
Motion sickness amelioration induced by prism spectacles
A side effect of the prescription of prism glasses according to the principle of Utermöhlen to improve mechanical reading skills of certain types of learning disabled children was the alleviation of
Slow deep breathing prevents the development of tachygastria and symptoms of motion sickness.
In conclusion, slow deep breathing in a situation previously demonstrated to provoke tachygastria prevented the development of gastric dysrhythmias and decreased symptoms of motion sickness.